Takashi Fujita Selected Research

Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)

1/2016	Impaired Antiviral Stress Granule and IFN-β Enhanceosome Formation Enhances Susceptibility to Influenza Infection in Chronic Obstructive Pulmonary Disease Epithelium.
8/2015	Functional IRF3 deficiency in a patient with herpes simplex encephalitis.
11/2012	Impairment of interferon regulatory factor-3 activation by hepatitis C virus core protein basic amino acid region 1.
6/2010	Aberrant expression of interferon regulatory factor 3 in human lung cancer.
1/2007	Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.
1/2006	Expression of IP-10/CXCL10 is upregulated by double-stranded RNA in BEAS-2B bronchial epithelial cells.
6/2002	Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex.

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Takashi Fujita Research Topics

Disease

41	Virus Diseases (Viral Diseases) 09/2020 - 03/2004
28	Infections 02/2022 - 01/2002
25	Neoplasms (Cancer) 02/2022 - 05/2006
16	Melanoma (Melanoma, Malignant) 09/2017 - 09/2005
12	Breast Neoplasms (Breast Cancer) 02/2022 - 01/2009
8	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2006
6	Prostatic Neoplasms (Prostate Cancer) 04/2021 - 11/2017
6	Wounds and Injuries (Trauma) 02/2020 - 12/2018
5	Porcine Reproductive and Respiratory Syndrome (PRRS) 10/2020 - 07/2006
4	Noninfiltrating Intraductal Carcinoma (DCIS) 12/2020 - 01/2019
3	Disease Progression 11/2021 - 08/2004
3	Lower Urinary Tract Symptoms 04/2021 - 01/2020
3	Necrosis 01/2021 - 09/2019
3	Human Influenza (Influenza) 01/2020 - 01/2012
3	Inflammation (Inflammations) 02/2018 - 01/2006
3	Ductal Carcinoma 03/2016 - 06/2006
3	Interstitial Lung Diseases (Interstitial Lung Disease) 05/2013 - 07/2009
2	Endocarditis 06/2022 - 10/2020
2	COVID-19 01/2022 - 09/2020
2	Vesicular Stomatitis 01/2022 - 12/2006
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2017
2	Severe Fever with Thrombocytopenia Syndrome 11/2021 - 01/2018
2	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 05/2009
2	Hepatocellular Carcinoma (Hepatoma) 10/2020 - 02/2005
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2014
2	Margins of Excision 01/2019 - 07/2014
2	Chronic Hepatitis C 01/2015 - 01/2011
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 12/2014 - 01/2006
2	RNA Virus Infections 01/2014 - 01/2010
2	Obesity 01/2014 - 02/2008
2	Dermatomyositis (Dermatopolymyositis) 05/2013 - 08/2012
2	Bites and Stings (Sting) 01/2013 - 02/2009
2	Amyopathic dermatomyositis 08/2012 - 07/2009
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2009 - 12/2006
1	Aortic Dissection 05/2022
1	Myocarditis (Carditis) 01/2022

Drug/Important Bio-Agent (IBA)

32	Antiviral Agents (Antivirals)IBA 02/2022 - 09/2005
24	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2021 - 09/2005
23	Proteins (Proteins, Gene)FDA Link 02/2022 - 12/2002
21	Interferon Type IIBA 01/2021 - 06/2002
15	CytokinesIBA 01/2022 - 04/2002
13	InterferonsIBA 10/2019 - 03/2005
8	RNA (Ribonucleic Acid)IBA 01/2021 - 02/2005
8	Viral RNAIBA 10/2020 - 09/2005
7	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 01/2016 - 06/2002
6	Messenger RNA (mRNA)IBA 02/2022 - 06/2006
6	Transcription Factors (Transcription Factor)IBA 12/2020 - 03/2004
6	Pattern Recognition ReceptorsIBA 08/2015 - 07/2006
6	RNA Helicases (RNA Helicase)IBA 01/2011 - 03/2007
6	Nucleic AcidsIBA 01/2010 - 07/2006
5	ChemokinesIBA 01/2022 - 04/2002
5	Small Interfering RNA (siRNA)IBA 10/2020 - 05/2006
5	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 07/2006
4	LigandsIBA 01/2021 - 08/2009
4	Phenobarbital (Luminal)FDA Link 10/2020 - 12/2012
3	AnthracyclinesIBA 02/2022 - 10/2010
3	Immunoglobulin G (IgG)IBA 01/2022 - 01/2019
3	Hormones (Hormone)IBA 12/2020 - 04/2012
3	Protein Kinases (Protein Kinase)IBA 10/2020 - 01/2016
3	Trastuzumab (Herceptin)FDA Link 07/2019 - 01/2009
3	Carrier Proteins (Binding Protein)IBA 12/2014 - 12/2002
3	AutoantibodiesIBA 05/2013 - 07/2009
2	Anti-Bacterial Agents (Antibiotics)IBA 06/2022 - 10/2020
2	taxaneIBA 02/2022 - 10/2010
2	LigninIBA 01/2022 - 09/2020
2	Tadalafil (Cialis)FDA Link 04/2021 - 01/2020
2	AntibodiesIBA 01/2021 - 09/2020
2	fucoxanthinIBA 03/2020 - 09/2016
2	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 01/2019
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019 - 10/2010
2	Complement System Proteins (Complement)IBA 01/2019 - 01/2012
2	Interferon LambdaIBA 01/2018 - 03/2007
2	Cardiac MyosinsIBA 12/2014 - 01/2006
2	LipidsIBA 01/2014 - 07/2008
2	Complementary DNA (cDNA)IBA 12/2012 - 07/2009
2	Poly I-CIBA 11/2012 - 12/2006
2	I-kappa B KinaseIBA 06/2010 - 02/2005
2	DNA (Deoxyribonucleic Acid)IBA 08/2009 - 07/2008
2	Indicators and Reagents (Reagents)IBA 07/2008 - 02/2008
2	NF-kappa B (NF-kB)IBA 01/2007 - 02/2005
2	Phosphotransferases (Kinase)IBA 02/2005 - 03/2004
1	Bio-glueIBA 05/2022
1	Taxoids (Taxanes)IBA 02/2022
1	VaccinesIBA 01/2022
1	oxidized low density lipoproteinIBA 01/2022
1	LDL CholesterolIBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	BNT162 VaccineIBA 01/2022
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2022

Therapy/Procedure

15	Therapeutics 06/2022 - 03/2005
6	Prostatectomy (Retropubic Prostatectomy) 04/2021 - 01/2018
6	Nephrectomy 01/2018 - 12/2006
5	Drug Therapy (Chemotherapy) 02/2022 - 03/2014
3	Radiotherapy 01/2018 - 07/2014
2	Sutures (Suture) 05/2022 - 10/2020
2	Laparotomy 01/2019 - 12/2018
2	Kidney Transplantation 01/2019 - 07/2010
2	Thoracotomy 01/2019 - 12/2018
2	Segmental Mastectomy (Lumpectomy) 07/2014 - 03/2014
2	Aftercare (After-Treatment) 01/2012 - 02/2008